SCHEMBL13624511

SCHEMBL13624511

CCC(=O)OCC(=O)Nc1ccc(OC(=O)CCCCCCCOCC(=O)Oc2ccc(NC(=O)COC(=O)CC)cc2)cc1

nearest known ligand 0.45

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.45
KMT2A Q03164 4/20 0.45
KLK7 P49862 2/20 0.44
ATM Q13315 2/20 0.44
MAPK1 P28482 1/20 0.44
MAPT P10636 6/20 0.44
GAA P10253 2/20 0.44
PKM P14618 1/20 0.44
RAB9A P51151 3/20 0.43
HTT P42858 2/20 0.43
LMNA P02545 1/20 0.43
SMN1; SMN2 Q16637 2/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
POLB P06746 2/20 0.41
ALDH1A1 P00352 2/20 0.41
NPC1 O15118 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13611346 1.00 MEN1 (0.45) MEN1KMT2AKLK7ATMMAPK1
SCHEMBL13611345 0.89 KLK7 (0.51) MEN1KMT2AKLK7ATMMAPK1
SCHEMBL13611342 0.87 KLK7 (0.53) MEN1KMT2AKLK7ATMMAPK1
SCHEMBL13611347 0.85 ATM (0.44) MEN1KMT2AKLK7ATMMAPK1
SCHEMBL13624512 0.85 ATM (0.44) MEN1KMT2AKLK7ATMMAPK1
SCHEMBL13611339 0.83 MAPT (0.59) MEN1KMT2AATMMAPK1MAPT
SCHEMBL10121479 0.75 ROCK2 (0.39) MEN1KMT2AKLK7ATMMAPK1
SCHEMBL13611343 0.75 KLK7 (0.47) MEN1KMT2AKLK7ATMMAPK1
SCHEMBL10301416 0.73 KMT2A (0.47) MEN1KMT2AMAPTGAARAB9A
SCHEMBL3438966 0.73 PRSS1 (0.60) MEN1KMT2AMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8309132-B2 Bioabsorbable polyesteramides and uses thereof BEZWADA BIOMEDICAL, LLC (US) 2012-11-13 US disclosed
US-20090285896-A1 BIOABSORBABLE POLYESTERAMIDES AND USES THEREOF BEZWADA BIOMEDICAL, LLC (US) 2009-11-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090285896-A1 BIOABSORBABLE POLYESTERAMIDES AND USES THEREOF PAICS, UROD, PUF60 MEN1 162/4885KMT2A 1362/4885KLK7 1948/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.