Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 13/20 | 0.62 |
| ▸ | NFE2L2 | Q16236 | 13/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | NAAA | Q02083 | 1/20 | 0.44 |
| ▸ | MIF | P14174 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL92951 | 0.76 | KEAP1 (0.60) | KEAP1NFE2L2KMT2ANAAAMIF | |
| SCHEMBL81704 | 0.75 | KEAP1 (0.58) | KEAP1NFE2L2NAAAMIF | |
| SCHEMBL17229157 | 0.75 | MEN1 (1.00) | MEN1KMT2ANAAARECQL | |
| SCHEMBL10101148 | 0.75 | MEN1 (0.89) | MEN1KMT2ANAAARECQL | |
| SCHEMBL6476918 | 0.73 | KEAP1 (0.66) | KEAP1NFE2L2NAAAMIF | |
| SCHEMBL17274366 | 0.73 | FAAH (0.56) | KEAP1NFE2L2NAAA | |
| SCHEMBL4394729 | 0.73 | KEAP1 (0.55) | KEAP1NFE2L2MEN1KMT2A | |
| SCHEMBL9259257 | 0.73 | MEN1 (0.94) | MEN1KMT2ANAAARECQL | |
| SCHEMBL21765846 | 0.73 | MEN1 (0.94) | MEN1KMT2ANAAARECQL | |
| SCHEMBL11758762 | 0.73 | MEN1 (0.94) | MEN1KMT2ANAAARECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1668050-B1 | ATTACHMENT OF MOLECULES TO SURFACES | SURMODICS INC (US) | 2009-11-11 | — | — | EP | disclosed |