Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 16/20 | 0.58 |
| ▸ | NFE2L2 | Q16236 | 16/20 | 0.58 |
| ▸ | MIF | P14174 | 3/20 | 0.37 |
| ▸ | NAAA | Q02083 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | BACH1 | O14867 | 1/20 | 0.37 |
| ▸ | MAFK | O60675 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL33517 | 0.84 | KEAP1 (0.40) | KEAP1NFE2L2 | |
| SCHEMBL465655 | 0.79 | KEAP1 (0.42) | KEAP1NFE2L2 | |
| SCHEMBL19998248 | 0.78 | KDM4E (0.37) | KEAP1NFE2L2 | |
| SCHEMBL16803277 | 0.78 | KDM4E (0.37) | KEAP1NFE2L2 | |
| SCHEMBL19988824 | 0.78 | KEAP1 (0.41) | KEAP1NFE2L2ALDH1A1 | |
| SCHEMBL907569 | 0.77 | KDM4E (0.52) | ALDH1A1 | |
| SCHEMBL632876 | 0.77 | KDM4E (0.46) | ALDH1A1 | |
| SCHEMBL14865406 | 0.77 | KDM4E (0.35) | KEAP1NFE2L2 | |
| SCHEMBL13624926 | 0.75 | KEAP1 (0.62) | KEAP1NFE2L2MIFNAAA | |
| SCHEMBL59429 | 0.75 | KDM4E (0.56) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8129159-B2 | Attachment of molecules to surfaces | SURMODICS, INC. (US) | 2012-03-06 | — | — | US | disclosed |
| US-8129159-B2 | Attachment of molecules to surfaces | SURMODICS, INC. (US) | 2012-03-06 | — | — | US | disclosed |
| US-8129159-B2 | Attachment of molecules to surfaces | SURMODICS, INC. (US) | 2012-03-06 | — | — | US | disclosed |
| US-20120010707-A1 | METHODS AND REAGENTS FOR PREPARING BIOMOLECULE-CONTAINING COATINGS | Surmodics Coatings, LLC | 2012-01-12 | — | — | US | disclosed |
| US-20110009292-A1 | ATTACHMENT OF MOLECULES TO SURFACES | SURMODICS, INC. (US) | 2011-01-13 | — | — | US | disclosed |
| US-20110009292-A1 | ATTACHMENT OF MOLECULES TO SURFACES | SURMODICS, INC. (US) | 2011-01-13 | — | — | US | disclosed |
| US-20110009292-A1 | ATTACHMENT OF MOLECULES TO SURFACES | SURMODICS, INC. (US) | 2011-01-13 | — | — | US | disclosed |
| US-7829317-B2 | Attachment of molecules to surfaces | SURMODICS, INC. (US) | 2010-11-09 | — | — | US | disclosed |
| US-7829317-B2 | Attachment of molecules to surfaces | SURMODICS, INC. (US) | 2010-11-09 | — | — | US | disclosed |
| US-7829317-B2 | Attachment of molecules to surfaces | SURMODICS, INC. (US) | 2010-11-09 | — | — | US | disclosed |
| US-20090042742-A1 | Attachment of molecules to surfaces | SURMODICS, INC. (US) | 2009-02-12 | — | — | US | disclosed |
| US-20090042742-A1 | Attachment of molecules to surfaces | SURMODICS, INC. (US) | 2009-02-12 | — | — | US | disclosed |
| US-7309593-B2 | Attachment of molecules to surfaces | SURMODICS, INC. (US) | 2007-12-18 | — | — | US | disclosed |
| US-7309593-B2 | Attachment of molecules to surfaces | SURMODICS, INC. (US) | 2007-12-18 | — | — | US | disclosed |
| US-7309593-B2 | Attachment of molecules to surfaces | SURMODICS, INC. (US) | 2007-12-18 | — | — | US | disclosed |
| EP-1668050-A2 | ATTACHMENT OF MOLECULES TO SURFACES | SurModics, Inc. (US) | 2006-06-14 | — | — | EP | disclosed |
| US-20050281857-A1 | Methods and reagents for preparing biomolecule-containing coatings | Surmodics Coatings, LLC | 2005-12-22 | — | — | US | disclosed |
| WO-2005115490-A2 | NATURAL BIODEGRADABLE POLYSACCHARIDE COATINGS FOR MEICAL ARTICLES | SURMODICS, INC. (US) | 2005-12-08 | — | — | WO | disclosed |
| WO-2005033158-A2 | ATTACHMENT OF MOLECULES TO SURFACES | SURMODICS, INC. (US) | 2005-04-14 | — | — | WO | disclosed |
| US-20050074478-A1 | Attachment of molecules to surfaces | SURMODICS, INC. (US) | 2005-04-07 | — | — | US | disclosed |