Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | RECQL | P46063 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | PADI3 | Q9ULW8 | 1/20 | 0.51 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.51 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.49 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.49 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.49 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | CTSK | P43235 | 1/20 | 0.48 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.48 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.48 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.48 |
| ▸ | MGLL | Q99685 | 1/20 | 0.48 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.47 |
| ▸ | MMP1 | P03956 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17864889 | 0.91 | MGLL (0.57) | NPC1RECQLRAB9ASMN1; SMN2LMNA | |
| SCHEMBL17342588 | 0.91 | PADI3 (0.53) | NPC1RECQLRAB9ASMN1; SMN2LMNA | |
| SCHEMBL17346754 | 0.91 | LMNA (0.56) | SMN1; SMN2LMNAPADI3PADI4MGLL | |
| SCHEMBL17342584 | 0.90 | HDAC3 (0.52) | NPC1RECQLRAB9ASMN1; SMN2LMNA | |
| SCHEMBL17342589 | 0.85 | ALDH1A1 (0.50) | SMN1; SMN2LMNAPADI3PADI4 | |
| SCHEMBL17346792 | 0.85 | TSHR (0.53) | SMN1; SMN2LMNAPADI3PADI4 | |
| SCHEMBL18124425 | 0.84 | HDAC1 (0.53) | NPC1RECQLRAB9ASMN1; SMN2PADI3 | |
| SCHEMBL17342601 | 0.84 | TSHR (0.55) | SMN1; SMN2LMNAPADI3PADI4 | |
| SCHEMBL17342586 | 0.84 | RAB9A (0.65) | NPC1RECQLRAB9ASMN1; SMN2LMNA | |
| SCHEMBL18124427 | 0.84 | HDAC1 (0.51) | NPC1RAB9ASMN1; SMN2LMNAPADI3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7622526-B2 | Thermoset material based on antiplasticizing polythiourethane and ophthalmic lens comprising an antiplasticized thermoset material | ESSILOR INTERNATIONAL (FR) | 2009-11-24 | — | — | US | disclosed |
| US-7622526-B2 | Thermoset material based on antiplasticizing polythiourethane and ophthalmic lens comprising an antiplasticized thermoset material | ESSILOR INTERNATIONAL (FR) | 2009-11-24 | — | — | US | disclosed |