Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNPAT | O15228 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | FNTA | P49354 | 5/20 | 0.38 |
| ▸ | FNTB | P49356 | 5/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.38 |
| ▸ | NOD1 | Q9Y239 | 3/20 | 0.38 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.36 |
| ▸ | ACE | P12821 | 1/20 | 0.36 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12509112 | 0.87 | GNPAT (0.43) | GNPATPTGS1GSTK1FOLH1ACE | |
| SCHEMBL15912290 | 0.87 | GNPAT (0.43) | GNPATPTGS1GSTK1FOLH1ACE | |
| SCHEMBL13625380 | 0.85 | GNPAT (0.47) | GNPATPTGS1GSTK1KDM4EMAPT | |
| SCHEMBL929193 | 0.83 | KDM4E (0.57) | GNPATPTGS1GSTK1KDM4EMAPT | |
| SCHEMBL13471896 | 0.82 | DNM1 (0.36) | GNPATPTGS1GSTK1KDM4EMAPT | |
| SCHEMBL13625463 | 0.82 | FOLH1 (0.53) | GNPATFNTAFNTBFOLH1NOD1 | |
| SCHEMBL11279985 | 0.82 | TGFBR1 (0.48) | GNPATPTGS1GSTK1KDM4EMAPT | |
| SCHEMBL928640 | 0.82 | GNPAT (0.47) | GNPATPTGS1GSTK1KDM4EMAPT | |
| SCHEMBL11269717 | 0.81 | MEN1 (0.47) | GNPATPTGS1GSTK1KDM4EMAPT | |
| SCHEMBL13625464 | 0.80 | FOLH1 (0.59) | GNPATFNTAFNTBFOLH1NOD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8937048-B2 | Anti-angiogenic compounds | COVX TECHNOLOGIES IRELAND, LIMITED (IE) | 2015-01-20 | — | — | US | disclosed |
| WO-2009136352-A1 | ANTI-ANGIOGENIC COMPOUNDS | COVX TECHNOLOGIES IRELAND, LTD. (IE) | 2009-11-12 | — | — | WO | disclosed |