Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNPAT | O15228 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | MME | P08473 | 3/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.39 |
| ▸ | ENPEP | Q07075 | 5/20 | 0.38 |
| ▸ | BMP1 | P13497 | 1/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.37 |
| ▸ | ACE | P12821 | 1/20 | 0.36 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.35 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12509112 | 1.00 | GNPAT (0.43) | GNPATCA2CA4MMEPTGS1 | |
| SCHEMBL19300016 | 0.88 | GNPAT (0.37) | GNPATCA2CA4MMEPTGS1 | |
| SCHEMBL13625379 | 0.87 | GNPAT (0.42) | GNPATCA2CA4PTGS1GSTK1 | |
| SCHEMBL11279926 | 0.84 | CA2 (0.55) | GNPATCA2CA4MMEPTGS1 | |
| SCHEMBL22415060 | 0.80 | FOLH1 (0.50) | GNPATCA2CA4MMEENPEP | |
| SCHEMBL25774753 | 0.78 | ACE (0.49) | GNPATCA2CA4MMEPTGS1 | |
| SCHEMBL9637071 | 0.78 | ACE (0.49) | GNPATCA2CA4MMEPTGS1 | |
| SCHEMBL17277187 | 0.78 | GNPAT (0.66) | GNPATCA2CA4MMEENPEP | |
| SCHEMBL29659587 | 0.77 | CA2 (0.51) | GNPATCA2CA4MMEENPEP | |
| SCHEMBL30797987 | 0.77 | CA2 (0.51) | GNPATCA2CA4MMEENPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9192682-B2 | Folate receptor binding conjugates of antifolates | ENDOCYTE, INC. (IN) | 2015-11-24 | — | — | US | disclosed |
| US-20140213760-A1 | Folate Receptor Binding Conjugates of Antifolates | ENDOCYTE, INC. (US) | 2014-07-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140213760-A1 | Folate Receptor Binding Conjugates of Antifolates | FOLR1, FOLR2, DHFR | GNPAT 494/4885CA2 4608/4885CA4 4556/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.