SCHEMBL1362552

SCHEMBL1362552

CCN1C(=O)N(C)C(=O)C1S

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 4/20 0.38
ALDH1A1 P00352 3/20 0.34
MAPT P10636 3/20 0.34
GAA P10253 3/20 0.34
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
HSD17B10 Q99714 2/20 0.34
THRB P10828 1/20 0.34
RECQL P46063 1/20 0.34
F2 P00734 1/20 0.33
ELANE P08246 1/20 0.33
CTSG P08311 1/20 0.33
CTRC Q99895 1/20 0.33
KDM4A O75164 2/20 0.33
KDM4C Q9H3R0 2/20 0.33
USP2 O75604 1/20 0.33
POLB P06746 1/20 0.33
ALOX15 P16050 1/20 0.33
TP53 P04637 1/20 0.32
PDE4B Q07343 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1361097 0.85 GAA (0.35) L3MBTL1ALDH1A1MAPTGAAMEN1
SCHEMBL1362917 0.82 GAA (0.50) L3MBTL1ALDH1A1MAPTGAAMEN1
SCHEMBL1362157 0.78 F2 (0.44) L3MBTL1ALDH1A1MAPTGAAF2
SCHEMBL1361335 0.75 L3MBTL1 (0.35) L3MBTL1ALDH1A1MAPTGAAF2
SCHEMBL6662381 0.74 L3MBTL1 (0.38) L3MBTL1ALDH1A1MAPTGAAMEN1
SCHEMBL1362580 0.72 ADRA2C (0.39) ALDH1A1MAPTMEN1KMT2A
SCHEMBL25405840 0.71 L3MBTL1 (0.35) L3MBTL1ALDH1A1MAPTGAAF2
SCHEMBL23709035 0.71 PDE4B (0.36) L3MBTL1ALDH1A1MAPTGAAMEN1
SCHEMBL1364181 0.69 F2 (0.39) L3MBTL1ALDH1A1MAPTGAAF2
SCHEMBL1361363 0.67 GAA (0.47) L3MBTL1GAAF2ELANECTSG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8066977-B2 Agent for permanent hair waving containing heterocyclic mercapto compound SHOWA DENKO K.K. (JP) 2011-11-29 US disclosed
CN-101184528-B Permanent waving agent containing heterocyclic mercapto compound SHOWA DENKO KK 2010-12-29 CN disclosed
EP-1883454-B1 AGENT FOR PERMANENT HAIR WAVING CONTAINING HETEROCYCLIC MERCAPTO COMPOUND SHOWA DENKO KK (JP) 2009-11-04 EP disclosed
US-20090208439-A1 Agent for Permanent Hair Waving Containing Heterocyclic Mercapto Compound SHOWA DENKO K.K. (JP) 2009-08-20 US disclosed
CN-101184528-A Permanent waving agent containing heterocyclic mercapto compound SHOWA DENKO KK (JP) 2008-05-21 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090208439-A1 Agent for Permanent Hair Waving Containing Heterocyclic Mercapto Compound NSD3, WNT3, MSRB3 L3MBTL1 2623/4885ALDH1A1 165/4885MAPT 4607/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.