Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14986940 | 0.77 | ADRA2C (0.40) | ADRA2CKMT2AMEN1PABPC1MAPK1 | |
| SCHEMBL23635615 | 0.72 | ADRA2C (0.43) | ADRA2CKMT2AMEN1PABPC1MAPK1 | |
| SCHEMBL27722447 | 0.72 | ADRA2C (0.33) | ADRA2CKMT2A | |
| SCHEMBL1363993 | 0.72 | — | — | |
| SCHEMBL1364095 | 0.72 | F2 (0.44) | ADRA2CADORA3KMT2AALDH1A1MAPT | |
| SCHEMBL1362552 | 0.72 | L3MBTL1 (0.38) | KMT2AALDH1A1MAPTMEN1 | |
| SCHEMBL162704 | 0.70 | ADRA2C (0.41) | ADRA2CADORA3ADORA2AKMT2AADORA1 | |
| SCHEMBL11918894 | 0.70 | ADRA2C (0.41) | ADRA2CADORA3ADORA2AKMT2AADORA1 | |
| SCHEMBL1361097 | 0.70 | GAA (0.35) | KMT2AALDH1A1MAPTMEN1 | |
| SCHEMBL1361254 | 0.70 | GAA (0.35) | ADRA2CALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8066977-B2 | Agent for permanent hair waving containing heterocyclic mercapto compound | SHOWA DENKO K.K. (JP) | 2011-11-29 | — | — | US | disclosed |
| CN-101184528-B | Permanent waving agent containing heterocyclic mercapto compound | SHOWA DENKO KK | 2010-12-29 | — | — | CN | disclosed |
| EP-1883454-B1 | AGENT FOR PERMANENT HAIR WAVING CONTAINING HETEROCYCLIC MERCAPTO COMPOUND | SHOWA DENKO KK (JP) | 2009-11-04 | — | — | EP | disclosed |
| US-20090208439-A1 | Agent for Permanent Hair Waving Containing Heterocyclic Mercapto Compound | SHOWA DENKO K.K. (JP) | 2009-08-20 | — | — | US | disclosed |
| CN-101184528-A | Permanent waving agent containing heterocyclic mercapto compound | SHOWA DENKO KK (JP) | 2008-05-21 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090208439-A1 | Agent for Permanent Hair Waving Containing Heterocyclic Mercapto Compound | NSD3, WNT3, MSRB3 | ADRA2C 2509/4885ADORA3 433/4885ADORA2A 1833/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.