Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | NAAA | Q02083 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6932994 | 0.91 | ALDH1A1 (0.46) | ACHEKDM4EALDH1A1GAATSHR | |
| SCHEMBL8150036 | 0.84 | ACHE (0.36) | ACHECYP1A2NAAAKDM4EALDH1A1 | |
| SCHEMBL7286766 | 0.75 | NAAA (0.56) | CYP1A2NAAAKDM4ESIGMAR1 | |
| SCHEMBL8396951 | 0.75 | NAAA (0.37) | CYP1A2NAAASIGMAR1 | |
| SCHEMBL8395467 | 0.75 | NAAA (0.37) | CYP1A2NAAASIGMAR1 | |
| SCHEMBL8392445 | 0.73 | NAAA (0.36) | CYP1A2NAAASIGMAR1 | |
| SCHEMBL8395374 | 0.73 | NAAA (0.36) | CYP1A2NAAASIGMAR1 | |
| SCHEMBL8396468 | 0.72 | NAAA (0.35) | CYP1A2NAAASIGMAR1 | |
| SCHEMBL10153613 | 0.71 | USP19 (0.41) | ACHEKDM4EALDH1A1GAATSHR | |
| SCHEMBL8396156 | 0.71 | NAAA (0.34) | CYP1A2NAAASIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009136352-A1 | ANTI-ANGIOGENIC COMPOUNDS | COVX TECHNOLOGIES IRELAND, LTD. (IE) | 2009-11-12 | — | — | WO | disclosed |