Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.56 |
| ▸ | P2RX7 | Q99572 | 7/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.41 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.41 |
| ▸ | IDE | P14735 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13625680 | 0.85 | ALDH1A1 (0.62) | HSD11B1P2RX7ALDH1A1HTTPOLB | |
| SCHEMBL13637173 | 0.84 | CYP1A2 (0.61) | HSD11B1P2RX7ALDH1A1L3MBTL1HTT | |
| SCHEMBL21206530 | 0.76 | CYP2A6 (0.40) | ALDH1A1HTTPOLBMEN1KMT2A | |
| SCHEMBL5815710 | 0.69 | P2RX7 (0.61) | HSD11B1P2RX7ALDH1A1L3MBTL1POLB | |
| SCHEMBL4403632 | 0.69 | CNR2 (0.60) | HSD11B1P2RX7ALDH1A1HTTPOLB | |
| SCHEMBL6110896 | 0.69 | IDE (0.41) | P2RX7ALDH1A1L3MBTL1HTTMEN1 | |
| SCHEMBL13723103 | 0.69 | LMNA (0.62) | ALDH1A1HTTPOLBMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL6356629 | 0.69 | P2RX7 (0.60) | HSD11B1P2RX7ALDH1A1L3MBTL1POLB | |
| SCHEMBL13722780 | 0.68 | NAMPT (0.65) | — | |
| SCHEMBL23132271 | 0.68 | CYP2A6 (0.69) | CYP1A2CYP2C9CYP2C19CYP3A4CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7622452-B2 | C-9 alkenylidine bridged macrolides | ENANTA PHARMACEUTICALS, INC. (US) | 2009-11-24 | — | — | US | disclosed |
| US-20080119418-A1 | C-9 ALKENYLIDINE BRIDGED MACROLIDES | ENANTA PHARMACEUTICALS, INC. | 2008-05-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080119418-A1 | C-9 ALKENYLIDINE BRIDGED MACROLIDES | CYP2C9, CCR9, DPP9 | HSD11B1 613/4885P2RX7 866/4885ALDH1A1 732/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.