Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 4/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | P2RX7 | Q99572 | 7/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13625681 | 0.84 | HSD11B1 (0.56) | CYP1A2CYP2C19MEN1CYP2C9KMT2A | |
| SCHEMBL4408289 | 0.83 | ALDH1A1 (0.71) | CYP1A2CYP2C19MEN1CYP2C9KMT2A | |
| SCHEMBL4409130 | 0.74 | ALDH1A1 (0.64) | CYP1A2CYP2C19MEN1CYP2C9KMT2A | |
| SCHEMBL4407364 | 0.73 | ALDH1A1 (0.62) | CYP1A2CYP2C19MEN1CYP2C9KMT2A | |
| SCHEMBL8629015 | 0.73 | LMNA (0.43) | CYP1A2CYP2C19CYP2C9ALDH1A1L3MBTL1 | |
| SCHEMBL5815710 | 0.73 | P2RX7 (0.61) | HSD11B1ALDH1A1P2RX7L3MBTL1POLB | |
| SCHEMBL12394470 | 0.72 | ALDH1A1 (0.63) | MEN1KMT2AALDH1A1HTTPOLB | |
| SCHEMBL4413792 | 0.72 | ALDH1A1 (0.60) | CYP1A2CYP2C19MEN1CYP2C9KMT2A | |
| Hydrochloric Acid SCHEMBL6356629 | 0.72 | P2RX7 (0.60) | HSD11B1ALDH1A1P2RX7L3MBTL1POLB | |
| SCHEMBL12396047 | 0.71 | NAMPT (0.62) | CYP2C19CYP2C9CYP3A4CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7622452-B2 | C-9 alkenylidine bridged macrolides | ENANTA PHARMACEUTICALS, INC. (US) | 2009-11-24 | — | — | US | disclosed |
| US-20080119418-A1 | C-9 ALKENYLIDINE BRIDGED MACROLIDES | ENANTA PHARMACEUTICALS, INC. | 2008-05-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080119418-A1 | C-9 ALKENYLIDINE BRIDGED MACROLIDES | CYP2C9, CCR9, DPP9 | CYP1A2 117/4885CYP2C19 4/4885MEN1 3930/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.