Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 3/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13626312 | 0.72 | ALDH1A1 (0.41) | MTNR1AMTNR1BLMNA | |
| SCHEMBL5831381 | 0.69 | HTR5A (0.41) | LMNAKMT2AKDM4EMAPTCA1 | |
| SCHEMBL5831052 | 0.69 | HTR5A (0.38) | LMNAKMT2AKDM4EMAPTCA1 | |
| SCHEMBL14037744 | 0.66 | HDAC9 (0.41) | MTNR1AMTNR1BLMNAPOLBNPC1 | |
| SCHEMBL11165552 | 0.66 | ADRA2A (0.48) | MTNR1AMTNR1BCA1CA2ACHE | |
| SCHEMBL5831674 | 0.66 | DRD2 (0.39) | MTNR1AMTNR1BLMNAKDM4EMAPT | |
| SCHEMBL7772440 | 0.65 | MTNR1A (0.47) | MTNR1AMTNR1BMAPTCA1CA2 | |
| SCHEMBL19469485 | 0.65 | PIN1 (0.51) | MTNR1AMTNR1BKDM4EMAPTCA1 | |
| SCHEMBL19469557 | 0.65 | PIN1 (0.51) | MTNR1AMTNR1BKDM4EMAPTCA1 | |
| SCHEMBL19469648 | 0.65 | PIN1 (0.51) | MTNR1AMTNR1BKDM4EMAPTCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009138440-A1 | CARBAMOYL DERIVATIVES OF BICYCLIC CARBONYLAMINO-PYRAZOLES AS PRODRUGS | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2009-11-19 | — | — | WO | disclosed |