Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 7/20 | 0.35 |
| ▸ | SOS1 | Q07889 | 3/20 | 0.34 |
| ▸ | NAMPT | P43490 | 4/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.33 |
| ▸ | CDK7 | P50613 | 1/20 | 0.33 |
| ▸ | CDK13 | Q14004 | 1/20 | 0.33 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | CCR2 | P41597 | 1/20 | 0.32 |
| ▸ | CCR1 | P32246 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13627676 | 0.84 | CDK9 (0.37) | TRPV1SCN9A | |
| SCHEMBL13628370 | 0.83 | NPC1 (0.44) | NAMPTCCR1 | |
| SCHEMBL13627677 | 0.83 | TRPV1 (0.37) | CYP11B2TRPV1SOS1NAMPTCCR2 | |
| SCHEMBL13627655 | 0.80 | PDK4 (0.42) | SOS1NAMPTSCN9ACCR1 | |
| SCHEMBL13628373 | 0.79 | CCR2 (0.44) | CCR2CCR1 | |
| SCHEMBL29579841 | 0.76 | CYP11B2 (0.57) | CYP11B2SOS1NAMPTTLR7CDK7 | |
| SCHEMBL4153073 | 0.76 | CYP11B2 (0.57) | CYP11B2SOS1NAMPTTLR7CDK7 | |
| SCHEMBL18901687 | 0.72 | CYP11B2 (0.40) | CYP11B2TRPV1NAMPTCDK7CDK13 | |
| SCHEMBL3322750 | 0.70 | CYP11B2 (0.45) | CYP11B2TRPV1 | |
| SCHEMBL13627654 | 0.68 | CCR2 (0.48) | SOS1CCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7618970-B2 | 3-aminocyclopentanecarboxamides as modulators of chemokine receptors | INCYTE CORPORATION (US) | 2009-11-17 | — | — | US | disclosed |