Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.42 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.42 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.42 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | PLK1 | P53350 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13628672 | 0.76 | CYP2D6 (0.55) | CYP1A2ALDH1A1CYP2C19NPC1RAB9A | |
| SCHEMBL14066327 | 0.74 | GRIN2D (0.55) | CYP1A2ALDH1A1CYP2C19HRH3LMNA | |
| SCHEMBL13628956 | 0.74 | CYP2D6 (0.37) | CYP1A2ALDH1A1CYP2C19LMNAKDM4E | |
| SCHEMBL30201139 | 0.72 | CYP1A2 (0.61) | CYP1A2ALDH1A1CYP2C19HRH3LMNA | |
| SCHEMBL574013 | 0.72 | CYP1A2 (0.61) | CYP1A2ALDH1A1CYP2C19HRH3LMNA | |
| SCHEMBL13628671 | 0.72 | CYP1A2 (0.49) | CYP1A2ALDH1A1CYP2C19HRH3LMNA | |
| SCHEMBL19951056 | 0.70 | ALDH1A1 (0.46) | CYP1A2ALDH1A1CYP2C19HRH3LMNA | |
| SCHEMBL10771160 | 0.70 | HRH1 (0.57) | CYP1A2ALDH1A1CYP2C19HRH3LMNA | |
| SCHEMBL6938906 | 0.70 | HRH1 (0.57) | CYP1A2ALDH1A1CYP2C19HRH3LMNA | |
| SCHEMBL8662285 | 0.70 | CYP1A2 (0.53) | CYP1A2ALDH1A1CYP2C19HRH3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7612197-B2 | Reacting a nucleophil with OH group with an electrophil to form an adduct, reacting adduct with a reagent selected from oxidizing, sulfurizing or selenizing agents to produce hydroxy protected oligonucleotide, heating to deprotect hydroxy protecting group such as 2-(2-pyridyl)aminoethoxycarbonyl | The United States of America as repesented by the Secretary of the Department of Health and Human Services (US) | 2009-11-03 | — | — | US | disclosed |