SCHEMBL13629431

SCHEMBL13629431

Nc1cc2c(O)c(/N=N/c3ccc(/N=N/c4ccc5ccc(S(=O)(=O)O)cc5c4)c4ncccc34)c(S(=O)(=O)O)cc2cc1S(=O)(=O)O

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN11 Q06124 3/20 0.58
PTPN7 P35236 2/20 0.58
PTPRC P08575 1/20 0.58
ALOX15 P16050 1/20 0.58
PTPN1 P18031 1/20 0.58
PTPN6 P29350 1/20 0.58
PTPRJ Q12913 1/20 0.58
HSD17B10 Q99714 1/20 0.58
DUSP26 Q9BV47 1/20 0.58
GLO1 Q04760 3/20 0.50
ENPP2 Q13822 8/20 0.47
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
THRB P10828 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
CD40 P25942 1/20 0.46
CD40LG P29965 1/20 0.46
NPC1 O15118 1/20 0.46
RAB9A P51151 1/20 0.46
CASP6 P55212 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13629433 0.90 PTPRC (0.50) PTPN11PTPN7PTPRCALOX15PTPN1
SCHEMBL13629430 0.88 ATIC (0.51) PTPN11PTPN7PTPRCALOX15PTPN1
SCHEMBL13629429 0.88 MEN1 (0.51) PTPN11PTPN7PTPRCALOX15PTPN1
SCHEMBL13629216 0.86 ENPP2 (0.54) HSD17B10ENPP2MEN1KMT2ATHRB
SCHEMBL14339189 0.85 MEN1 (0.49) PTPN11PTPN7PTPRCALOX15PTPN1
SCHEMBL13629758 0.84 GLO1 (0.43) PTPN11PTPN7PTPRCALOX15PTPN1
SCHEMBL13629757 0.83 SENP2 (0.51) PTPN11PTPN7PTPRCALOX15PTPN1
SCHEMBL13629222 0.83 SENP2 (0.51) PTPN11PTPN7PTPRCALOX15PTPN1
SCHEMBL13629750 0.83 SENP2 (0.51) PTPN11PTPN7PTPRCALOX15PTPN1
SCHEMBL13615108 0.82 PTPN11 (0.60) PTPN11PTPN7PTPRCALOX15PTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090275742-A1 COLORING MATTER FOR ANISOTROPIC COLORING MATTER FILM, COMPOSITION COMPRISING SAID COLORING MATTER, ANISOTROPIC COLORING MATTER FILM, AND POLARIZING ELEMENT MITSUBISHI CHEMICAL CORPORATION (JP) 2009-11-05 US disclosed