SCHEMBL13629758

SCHEMBL13629758

Nc1cc2c(O)c(N=Nc3ccc(N=Nc4ccc5[nH]c(=O)[nH]c5c4)c4ncccc34)c(S(=O)(=O)O)cc2cc1S(=O)(=O)O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GLO1 Q04760 3/20 0.43
PTPN11 Q06124 3/20 0.43
PTPN7 P35236 2/20 0.43
PTPRC P08575 1/20 0.43
ALOX15 P16050 1/20 0.43
PTPN1 P18031 1/20 0.43
PTPN6 P29350 1/20 0.43
PTPRJ Q12913 1/20 0.43
HSD17B10 Q99714 1/20 0.43
DUSP26 Q9BV47 1/20 0.43
CYP1A2 P05177 3/20 0.41
HIF1A Q16665 2/20 0.41
HPGD P15428 1/20 0.41
MEN1 O00255 5/20 0.41
KMT2A Q03164 5/20 0.41
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
CASP6 P55212 1/20 0.41
ATM Q13315 1/20 0.41
KLF5 Q13887 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13629224 0.91 SENP2 (0.46) GLO1CYP1A2HIF1AMEN1KMT2A
SCHEMBL13615290 0.89 PTPN11 (0.47) GLO1PTPN11PTPN7PTPRCALOX15
SCHEMBL13629429 0.87 MEN1 (0.51) GLO1PTPN11PTPN7PTPRCALOX15
SCHEMBL13629430 0.86 ATIC (0.51) GLO1PTPN11PTPN7PTPRCALOX15
SCHEMBL13629431 0.84 PTPN11 (0.58) GLO1PTPN11PTPN7PTPRCALOX15
SCHEMBL14339189 0.84 MEN1 (0.49) GLO1PTPN11PTPN7PTPRCALOX15
SCHEMBL13629753 0.84 SENP3 (0.48) HSD17B10CYP1A2HIF1AMEN1KMT2A
SCHEMBL13629264 0.81 ENPP2 (0.48) ALOX15HSD17B10CYP1A2HPGDMEN1
SCHEMBL13629433 0.81 PTPRC (0.50) GLO1PTPN11PTPN7PTPRCALOX15
SCHEMBL13615307 0.79 PTPN11 (0.41) GLO1PTPN11CYP1A2HIF1AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090275742-A1 COLORING MATTER FOR ANISOTROPIC COLORING MATTER FILM, COMPOSITION COMPRISING SAID COLORING MATTER, ANISOTROPIC COLORING MATTER FILM, AND POLARIZING ELEMENT MITSUBISHI CHEMICAL CORPORATION (JP) 2009-11-05 US disclosed