Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 4/20 | 0.74 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | FFAR4 | Q5NUL3 | 5/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | GFER | P55789 | 1/20 | 0.58 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.57 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.57 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | BRD4 | O60885 | 1/20 | 0.55 |
| ▸ | PGR | P06401 | 1/20 | 0.55 |
| ▸ | CYTH2 | Q99418 | 1/20 | 0.55 |
| ▸ | ESR1 | P03372 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16325591 | 0.85 | PKM (1.00) | PKMCYP19A1ALDH1A1MAPTMEN1 | |
| SCHEMBL13629414 | 0.85 | MAPT (0.55) | PKMCYP19A1ALDH1A1MAPTMEN1 | |
| SCHEMBL13629345 | 0.85 | PGR (0.61) | PKMALDH1A1MEN1KMT2AFFAR4 | |
| SCHEMBL13629400 | 0.85 | CYP19A1 (0.61) | PKMCYP19A1ALDH1A1MAPTMEN1 | |
| SCHEMBL13629423 | 0.83 | CES1 (0.60) | PKMCYP19A1ALDH1A1MAPTFFAR4 | |
| SCHEMBL14602130 | 0.83 | PKM (0.78) | PKMCYP19A1ALDH1A1MAPTMEN1 | |
| SCHEMBL13629464 | 0.82 | ALDH1A1 (0.77) | ALDH1A1MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL790294 | 0.80 | GAA (0.86) | PKMCYP19A1ALDH1A1MAPTMEN1 | |
| SCHEMBL8752431 | 0.80 | UCHL1 (0.71) | PKMCYP19A1ALDH1A1MAPTMEN1 | |
| SCHEMBL6928661 | 0.80 | UCHL1 (0.71) | PKMCYP19A1ALDH1A1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090275593-A1 | 3 Substituted N-(aryl- or heteroaryl)-pyrazolo[1,5-a]pyrimidines as Kinase Inhibitors | NOVARTIS AG | 2009-11-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090275593-A1 | 3 Substituted N-(aryl- or heteroaryl)-pyrazolo[1,5-a]pyrimidines as Kinase Inhibitors | TIE1, TEK, MATK | PKM 446/4885CYP19A1 3220/4885ALDH1A1 2121/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.