Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 5/20 | 0.62 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | FPR2 | P25090 | 1/20 | 0.44 |
| ▸ | DRD1 | P21728 | 1/20 | 0.43 |
| ▸ | LDHA | P00338 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.41 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.41 |
| ▸ | TACR1 | P25103 | 2/20 | 0.41 |
| ▸ | MME | P08473 | 1/20 | 0.40 |
| ▸ | ACE | P12821 | 1/20 | 0.40 |
| ▸ | CPA1 | P15085 | 1/20 | 0.40 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.40 |
| ▸ | ITGAV | P06756 | 1/20 | 0.40 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25471843 | 0.89 | ITGB3 (0.49) | ALOX15ITGB3ITGA2BLMNAFPR2 | |
| SCHEMBL8259039 | 0.86 | ALOX15 (0.45) | ALOX15ITGB3ITGA2BLMNAFPR2 | |
| SCHEMBL13630689 | 0.83 | ALDH1A1 (0.61) | ALOX15ITGB3ITGA2BALDH1A1 | |
| SCHEMBL10425937 | 0.83 | LDHA (0.56) | ALOX15ITGB3ITGA2BLMNAFPR2 | |
| SCHEMBL9405347 | 0.83 | LDHA (0.56) | ALOX15ITGB3ITGA2BLMNAFPR2 | |
| SCHEMBL9819533 | 0.83 | LDHA (0.56) | ALOX15ITGB3ITGA2BLMNAFPR2 | |
| SCHEMBL7290022 | 0.83 | ITGB3 (0.51) | ITGB3ITGA2BLMNAFPR2LDHA | |
| SCHEMBL7290024 | 0.83 | ITGB3 (0.51) | ITGB3ITGA2BLMNAFPR2LDHA | |
| SCHEMBL3419160 | 0.82 | LDHA (0.66) | ALOX15ITGB3ITGA2BLMNAFPR2 | |
| SCHEMBL2516039 | 0.82 | LDHA (0.66) | ALOX15ITGB3ITGA2BLMNAFPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090285888-A1 | DERIVATIVES OF DIHYDROXYPHENYLALANINE | ELLNEUROXX LTD. (DE) | 2009-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090285888-A1 | DERIVATIVES OF DIHYDROXYPHENYLALANINE | HTT, NLN, SNCA | ALOX15 392/4885ITGB3 3691/4885ITGA2B 3932/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.