Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 4/20 | 0.33 |
| ▸ | KDM5A | P29375 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | KDM4A | O75164 | 1/20 | 0.30 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.30 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5209578 | 0.78 | EPHX2 (0.36) | EPHX2LMNAKDM4CKDM5AALDH1A1 | |
| SCHEMBL5211825 | 0.74 | ALDH1A1 (0.33) | EPHX2ALDH1A1 | |
| SCHEMBL16144753 | 0.74 | ALDH1A1 (0.30) | LMNAALDH1A1 | |
| SCHEMBL12656337 | 0.73 | FDPS (0.35) | MAPK1ALDH1A1 | |
| SCHEMBL25852449 | 0.72 | ALDH1A1 (0.48) | EPHX2LMNAALDH1A1CHRNB2CHRNB4 | |
| SCHEMBL14230055 | 0.72 | EPHX2 (0.42) | FAAHMEN1MAPK1KMT2AEPHX2 | |
| SCHEMBL5206114 | 0.70 | EPHX2 (0.41) | EPHX2LMNAKDM4CKDM5AALDH1A1 | |
| SCHEMBL5210955 | 0.70 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL5909180 | 0.70 | LMNA (0.57) | FAAHLMNAHSP90AA1PHF8KDM2A | |
| SCHEMBL14229082 | 0.69 | EPHX2 (0.50) | FAAHMEN1MAPK1KMT2AEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2119702-A1 | AMIDE DERIVATIVE | Dainippon Sumitomo Pharma Co., Ltd. (JP) | 2009-11-18 | — | — | EP | disclosed |