Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12656337 | 0.79 | FDPS (0.35) | ALDH1A1 | |
| SCHEMBL5210955 | 0.76 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL497599 | 0.75 | CA12 (0.33) | ALDH1A1LMNAMAPTSMN1; SMN2NPSR1 | |
| SCHEMBL13630924 | 0.74 | FAAH (0.35) | ALDH1A1LMNA | |
| SCHEMBL19068994 | 0.74 | MEN1 (0.35) | — | |
| SCHEMBL2825332 | 0.74 | CA2 (0.33) | — | |
| SCHEMBL8059768 | 0.74 | CA12 (0.32) | ALDH1A1LMNAMAPTSMN1; SMN2NPSR1 | |
| SCHEMBL497598 | 0.74 | CA12 (0.32) | — | |
| SCHEMBL5211825 | 0.73 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL7498907 | 0.73 | ALDH1A1 (0.48) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2451813-B1 | HETEROCYCLIC COMPOUNDS AS JAK RECEPTOR AND PROTEIN TYROSINE KINASE INHIBITORS | LEO PHARMA AS (DK) | 2014-10-01 | — | — | EP | disclosed |