Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.37 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13434258 | 1.00 | ALDH1A1 (0.41) | ALDH1A1L3MBTL1KMT2APKMHTT | |
| SCHEMBL3488949 | 0.89 | KMT2A (0.45) | ALDH1A1L3MBTL1KMT2APKMHTT | |
| SCHEMBL3488955 | 0.89 | KMT2A (0.45) | ALDH1A1L3MBTL1KMT2APKMHTT | |
| SCHEMBL13434254 | 0.82 | CYP3A4 (0.47) | ALDH1A1L3MBTL1KMT2ASMN1; SMN2CYP3A4 | |
| SCHEMBL13434255 | 0.81 | L3MBTL1 (0.45) | ALDH1A1L3MBTL1KMT2APKMHTT | |
| SCHEMBL13434257 | 0.75 | L3MBTL1 (0.41) | ALDH1A1L3MBTL1KMT2APKMHTT | |
| SCHEMBL13434256 | 0.75 | L3MBTL1 (0.41) | ALDH1A1L3MBTL1KMT2APKMHTT | |
| SCHEMBL13631102 | 0.75 | L3MBTL1 (0.41) | ALDH1A1L3MBTL1KMT2APKMHTT | |
| SCHEMBL7794347 | 0.75 | L3MBTL1 (0.41) | ALDH1A1L3MBTL1KMT2APKMHTT | |
| SCHEMBL29725628 | 0.74 | SIGMAR1 (0.56) | ALDH1A1L3MBTL1KMT2AMCHR1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2119702-A1 | AMIDE DERIVATIVE | Dainippon Sumitomo Pharma Co., Ltd. (JP) | 2009-11-18 | — | — | EP | disclosed |