Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3488955 | 1.00 | KMT2A (0.45) | KMT2AL3MBTL1PKMHTTSMN1; SMN2 | |
| SCHEMBL13631103 | 0.89 | ALDH1A1 (0.41) | KMT2AL3MBTL1PKMHTTSMN1; SMN2 | |
| SCHEMBL13434258 | 0.89 | ALDH1A1 (0.41) | KMT2AL3MBTL1PKMHTTSMN1; SMN2 | |
| SCHEMBL13434254 | 0.85 | CYP3A4 (0.47) | KMT2AL3MBTL1SMN1; SMN2MMP1MMP13 | |
| SCHEMBL13434255 | 0.84 | L3MBTL1 (0.45) | KMT2AL3MBTL1PKMHTTSMN1; SMN2 | |
| SCHEMBL29725628 | 0.77 | SIGMAR1 (0.56) | KMT2AL3MBTL1SIGMAR1ALDH1A1MEN1 | |
| SCHEMBL13088854 | 0.76 | KDM4E (0.53) | KMT2AL3MBTL1SIGMAR1 | |
| SCHEMBL25593840 | 0.75 | KMT2A (0.59) | KMT2AL3MBTL1SMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL25841821 | 0.75 | KMT2A (0.50) | KMT2AL3MBTL1SIGMAR1ALDH1A1CYP2C19 | |
| SCHEMBL7475783 | 0.75 | SIGMAR1 (0.65) | KMT2ASMN1; SMN2SIGMAR1ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100056497-A1 | AMIDE DERIVATIVE | DAINIPPON SUMITOMO PHARMA CO., LTD (JP) | 2010-03-04 | — | — | US | disclosed |
| EP-2119702-A1 | AMIDE DERIVATIVE | Dainippon Sumitomo Pharma Co., Ltd. (JP) | 2009-11-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100056497-A1 | AMIDE DERIVATIVE | REN, AGTR1, AGTR2 | KMT2A 921/4885L3MBTL1 3531/4885PKM 3687/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.