Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13434257 | 1.00 | L3MBTL1 (0.41) | L3MBTL1KMT2ACACNA1BALDH1A1OPRM1 | |
| SCHEMBL13631102 | 1.00 | L3MBTL1 (0.41) | L3MBTL1KMT2ACACNA1BALDH1A1OPRM1 | |
| SCHEMBL13434256 | 1.00 | L3MBTL1 (0.41) | L3MBTL1KMT2ACACNA1BALDH1A1OPRM1 | |
| SCHEMBL12353629 | 0.92 | KMT2A (0.43) | L3MBTL1KMT2AALDH1A1OPRK1CTSK | |
| SCHEMBL13088860 | 0.89 | L3MBTL1 (0.46) | L3MBTL1KMT2AALDH1A1CTSKSIGMAR1 | |
| SCHEMBL2816591 | 0.89 | L3MBTL1 (0.46) | L3MBTL1KMT2AALDH1A1CTSKSIGMAR1 | |
| SCHEMBL3487334 | 0.89 | L3MBTL1 (0.46) | L3MBTL1KMT2AALDH1A1CTSKSIGMAR1 | |
| SCHEMBL12361787 | 0.83 | ALDH1A1 (0.41) | L3MBTL1KMT2AALDH1A1OPRM1OPRK1 | |
| SCHEMBL13434260 | 0.83 | ALDH1A1 (0.41) | L3MBTL1KMT2AALDH1A1OPRM1OPRK1 | |
| SCHEMBL13630926 | 0.83 | ALDH1A1 (0.41) | L3MBTL1KMT2AALDH1A1OPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010150840-A1 | N-SUBSTITUTED-CYCLIC AMINO DERIVATIVE | 大日本住友製薬株式会社 (JP) | 2010-12-29 | — | — | WO | disclosed |
| US-20100056497-A1 | AMIDE DERIVATIVE | DAINIPPON SUMITOMO PHARMA CO., LTD (JP) | 2010-03-04 | — | — | US | disclosed |
| EP-2119702-A1 | AMIDE DERIVATIVE | Dainippon Sumitomo Pharma Co., Ltd. (JP) | 2009-11-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100056497-A1 | AMIDE DERIVATIVE | REN, AGTR1, AGTR2 | L3MBTL1 3531/4885KMT2A 921/4885CACNA1B 761/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.