Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | NHERF1 | O14745 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | ACR | P10323 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13633538 | 0.84 | METAP2 (0.54) | ALDH1A1LMNAGAAKMT2ARECQL | |
| SCHEMBL13789387 | 0.78 | KDM4E (0.50) | ALDH1A1SMN1; SMN2LMNAGAAKDM4E | |
| SCHEMBL13633458 | 0.77 | KDM4E (0.49) | ALDH1A1SMN1; SMN2LMNAGAAKMT2A | |
| SCHEMBL841568 | 0.75 | CYP1A2 (0.61) | ALDH1A1SMN1; SMN2GAAKMT2AKDM4E | |
| SCHEMBL1425164 | 0.71 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2KMT2AKDM4EMAPT | |
| SCHEMBL3177473 | 0.71 | LMNA (0.58) | ALDH1A1SMN1; SMN2LMNAGAAKMT2A | |
| SCHEMBL23200315 | 0.70 | LMNA (0.76) | ALDH1A1SMN1; SMN2LMNAGAAKMT2A | |
| SCHEMBL31138238 | 0.70 | LMNA (0.76) | ALDH1A1SMN1; SMN2LMNAGAAKMT2A | |
| SCHEMBL13868451 | 0.70 | MAPT (0.47) | ALDH1A1SMN1; SMN2LMNAGAAKMT2A | |
| SCHEMBL19787931 | 0.70 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2KMT2AHIF1AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090275577-A1 | IMIDAZOPYRIDINE AND IMIDAZOPYRIMIDINE DERIVATIVES AS ANTIBACTERIAL AGENTS | PFIZER INC | 2009-11-05 | — | — | US | disclosed |
| US-20070191394-A1 | Antibacterial agents | WARNER-LAMBERT COMPANY LLC | 2007-08-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070191394-A1 | Antibacterial agents | MRPL21, RPN2, FBL | ALDH1A1 637/4885SMN1; SMN2 2248/4885LMNA 2919/4885 |
| US-20090275577-A1 | IMIDAZOPYRIDINE AND IMIDAZOPYRIMIDINE DERIVATIVES AS ANTIBACTERIAL AGENTS | DPYD, TYMP, ITPA | ALDH1A1 272/4885SMN1; SMN2 1846/4885LMNA 3979/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.