SCHEMBL641602

SCHEMBL641602

Cc1cc(C(=O)ON2C(=O)CCC2=O)cc(C)c1OC(=O)c1c2ccccc2[n+](C)c2ccccc12

nearest known ligand 0.32

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 2/20 0.32
HTT P42858 3/20 0.32
GAA P10253 2/20 0.32
KDM4E B2RXH2 2/20 0.32
TP53 P04637 1/20 0.32
MAPT P10636 1/20 0.32
HSD17B10 Q99714 1/20 0.32
KMT2A Q03164 7/20 0.31
PKM P14618 2/20 0.31
LMNA P02545 2/20 0.31
ALDH1A1 P00352 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
PREP P48147 1/20 0.31
PSMB8 P28062 1/20 0.31
PSMB5 P28074 1/20 0.31
PPARA Q07869 1/20 0.31
MAPK1 P28482 1/20 0.31
CYP2C19 P33261 1/20 0.30
MGLL Q99685 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31163697 1.00 ACHE (0.32) ACHEHTTGAAKDM4ETP53
SCHEMBL4194167 0.93 KDM4E (0.32) ACHEHTTGAAKDM4ETP53
SCHEMBL8910403 0.92 TERT (0.36) KDM4EPKMLMNAALDH1A1
SCHEMBL29373064 0.92 TERT (0.36) KDM4EPKMLMNAALDH1A1
Trifluoromethanesulfonic Acid SCHEMBL21542360 0.91 ACHE (0.31) ACHE
SCHEMBL13633675 0.88 ACHE (0.33) ACHETP53MAPTKMT2A
SCHEMBL7531675 0.88
SCHEMBL4187500 0.88 POLB (0.31) ACHETP53MAPTKMT2A
SCHEMBL17898188 0.86 KDM4E (0.36) GAAKDM4EMAPTHSD17B10LMNA
SCHEMBL4535032 0.85 KMT2A (0.39) KDM4EMAPTHSD17B10KMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11932603-B2 Hydrophilic high quantum yield acridinium esters with improved stability and fast light emission SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) 2024-03-19 US disclosed
US-20220227711-A1 HYDROPHILIC HIGH QUANTUM YIELD ACRIDINIUM ESTERS WITH IMPROVED STABILITY AND FAST LIGHT EMISSION SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) 2022-07-21 US disclosed
US-11332445-B2 Hydrophilic high quantum yield acridinium esters with improved stability and fast light emission SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) 2022-05-17 US disclosed
US-20200190037-A1 HYDROPHILIC HIGH QUANTUM YIELD ACRIDINIUM ESTERS WITH IMPROVED STABILITY AND FAST LIGHT EMISSION SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) 2020-06-18 US disclosed
EP-3019575-B1 HYDROPHILIC HIGH QUANTUM YIELD ACRIDINIUM ESTERS WITH IMPROVED STABILITY AND FAST LIGHT EMISSION SIEMENS HEALTHCARE DIAGNOSTICS INC (US) 2018-12-19 EP disclosed
EP-3067345-B1 ZWITTERION-CONTAINING ACRIDINIUM COMPOUNDS SIEMENS HEALTHCARE DIAGNOSTICS INC (US) 2018-09-05 EP disclosed
US-20170320830-A1 HYDROPHILIC HIGH QUANTUM YIELD ACRIDINIUM ESTERS WITH IMPROVED STABILITY AND FAST LIGHT EMISSION SIEMENS HEALTHCARE DIAGNOSTICS INC. 2017-11-09 US disclosed
US-20170320830-A1 HYDROPHILIC HIGH QUANTUM YIELD ACRIDINIUM ESTERS WITH IMPROVED STABILITY AND FAST LIGHT EMISSION SIEMENS HEALTHCARE DIAGNOSTICS INC. 2017-11-09 US disclosed
US-20170320830-A1 HYDROPHILIC HIGH QUANTUM YIELD ACRIDINIUM ESTERS WITH IMPROVED STABILITY AND FAST LIGHT EMISSION SIEMENS HEALTHCARE DIAGNOSTICS INC. 2017-11-09 US disclosed
US-9575062-B2 Zwitterion-containing acridinium compounds SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) 2017-02-21 US disclosed
US-20100099077-A1 STABLE ACRIDINIUM ESTERS WITH FAST LIGHT EMISSION SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) 2010-04-22 US disclosed
US-20090318627-A1 SOLID PHASE SYNTHESIS OF ACRIDINIUM DERIVATIVES SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) 2009-12-24 US disclosed
US-20090318627-A1 SOLID PHASE SYNTHESIS OF ACRIDINIUM DERIVATIVES SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) 2009-12-24 US disclosed
US-20080014660-A1 High Quantum Yield Acridinium Compounds and Their Uses in Improving Assay Sensitivity BAYER HEALTHCARE LLC 2008-01-17 US disclosed
US-20080014660-A1 High Quantum Yield Acridinium Compounds and Their Uses in Improving Assay Sensitivity BAYER HEALTHCARE LLC 2008-01-17 US disclosed
US-20080014660-A1 High Quantum Yield Acridinium Compounds and Their Uses in Improving Assay Sensitivity BAYER HEALTHCARE LLC 2008-01-17 US disclosed
US-7309615-B2 High quantum yield acridinium compounds and their uses in improving assay sensitivity SIEMENS MEDICAL SOLUTIONS DIAGNOSTIC (US) 2007-12-18 US disclosed
US-7309615-B2 High quantum yield acridinium compounds and their uses in improving assay sensitivity SIEMENS MEDICAL SOLUTIONS DIAGNOSTIC (US) 2007-12-18 US disclosed
WO-2007092847-A2 SOLID PHASE SYNTHESIS OF ACRIDINIUM DERIVATIVES SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) 2007-08-16 WO disclosed
US-20050221390-A1 High quantum yield acridinium compounds and their uses in improving assay sensitivity BAYER HEALTHCARE LLC (US) 2005-10-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200190037-A1 HYDROPHILIC HIGH QUANTUM YIELD ACRIDINIUM ESTERS WITH IMPROVED STABILITY AND FAST LIGHT EMISSION ACR, HACD3, FCGR3B ACHE 860/4885HTT 412/4885GAA 710/4885
US-20170320830-A1 HYDROPHILIC HIGH QUANTUM YIELD ACRIDINIUM ESTERS WITH IMPROVED STABILITY AND FAST LIGHT EMISSION ACR, HACD3, FCGR3B ACHE 860/4885HTT 412/4885GAA 710/4885
US-11332445-B2 Hydrophilic high quantum yield acridinium esters with improved stability and fast light emission ACR, HACD3, FCGR3B ACHE 860/4885HTT 412/4885GAA 710/4885
US-20220227711-A1 HYDROPHILIC HIGH QUANTUM YIELD ACRIDINIUM ESTERS WITH IMPROVED STABILITY AND FAST LIGHT EMISSION ACR, HACD3, FCGR3B ACHE 860/4885HTT 412/4885GAA 710/4885
US-20100099077-A1 STABLE ACRIDINIUM ESTERS WITH FAST LIGHT EMISSION ACR, NAALAD2, CES2 ACHE 693/4885HTT 1427/4885GAA 69/4885
US-20090318627-A1 SOLID PHASE SYNTHESIS OF ACRIDINIUM DERIVATIVES ACR, SSU72, SP1 ACHE 2066/4885HTT 2887/4885GAA 3503/4885
US-11932603-B2 Hydrophilic high quantum yield acridinium esters with improved stability and fast light emission ACR, HACD3, FCGR3B ACHE 860/4885HTT 412/4885GAA 710/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.