SCHEMBL8910403

SCHEMBL8910403

COS(=O)(=O)[O-].Cc1cc(C(=O)ON2C(=O)CCC2=O)cc(C)c1OC(=O)c1c2ccccc2[n+](C)c2ccccc12

nearest known ligand 0.36

Known targets — ChEMBL curated mechanism

ACHECHRM1CHRM3

The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TERT O14746 1/20 0.36
LMNA P02545 1/20 0.33
KDM4E B2RXH2 1/20 0.30
ALDH1A1 P00352 1/20 0.30
PKM P14618 1/20 0.30
HPGD P15428 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29373064 1.00 TERT (0.36) TERTLMNAKDM4EALDH1A1PKM
SCHEMBL31163697 0.92 ACHE (0.32) LMNAKDM4EALDH1A1PKM
SCHEMBL641602 0.92 ACHE (0.32) LMNAKDM4EALDH1A1PKM
Trifluoromethanesulfonic Acid SCHEMBL21542360 0.91 ACHE (0.31)
SCHEMBL7531675 0.88
SCHEMBL4194167 0.86 KDM4E (0.32) LMNAKDM4EALDH1A1PKMHPGD
SCHEMBL19564423 0.83 ALDH1A1 (0.37) KDM4EALDH1A1PKMHPGDSMN1; SMN2
SCHEMBL7781667 0.82 TERT (0.38) TERTLMNA
SCHEMBL4535032 0.81 KMT2A (0.39) LMNAKDM4EALDH1A1HPGD
SCHEMBL13633675 0.81 ACHE (0.33) SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4749284-A1 DETERMINATION OF FREE THYROID HORMONE pes Diagnosesysteme GmbH (DE) 2026-05-27 EP disclosed
US-20240353412-A1 A METHOD AND REAGENTS FOR ENHANCING THE CHEMILUMINESCENT SIGNAL EUROIMMUN MEDIZINISCHE LABORDIAGNOSTIKA AG (DE) 2024-10-24 US disclosed
CN-116925042-A DMAE acridine ester and preparation method and application thereof 上海品峰医疗科技有限公司 2023-10-24 CN disclosed
CN-114184604-A Kit for detecting neurofilament light chain, method and application thereof 深圳上泰生物工程有限公司 2022-03-15 CN disclosed
CN-105866433-A Detection method for NY-ESO-1 autoantibodies in peripheral blood 浙江大学 2016-08-17 CN disclosed
US-5656500-A LIPOSOMES COUPLED TO MOLECULES WITH BIOLOGICAL ACTIVITY SELECTED FROM ANTIGENS, ANTIBODIES, AND NUCLEIC ACIDS, THESE CONJUGATE ENCAPSULATE HYDROPHILIC POLYSUBSTITUTED ARYL ACRIDINIUM ESTERS CHIRON DIAGNOSTICS CORPORATION (US) 1997-08-12 US disclosed
US-5595875-A DNA, RNA, IMMUNOASSAY, CHEMILUMINESCENCE CIBA CORNING DIAGNOSTICS CORP. (US) 1997-01-21 US disclosed
EP-0353971-B1 Acridinium esters and method for detection of an analyte using acridinium esters and liposomes CIBA CORNING DIAGNOSTICS CORP (US) 1996-02-07 EP disclosed
US-5449556-A Chemiluminescent markers CIBA CORNING DIAGNOSTICS CORP. (US) 1995-09-12 US disclosed
US-5227489-A Hydrophilic chemiluminescent markers CIBA CORNING DIAGNOSTICS CORP. (US) 1993-07-13 US disclosed
EP-0263657-B1 POLYSUBSTITUTED ARYL ACRIDINIUM ESTERS Ciba Corning Diagnostics Corp. (US) 1992-05-13 EP disclosed
US-5110932-A Chemiluminescent immunoassay CIBA CORNING DIAGNOSTICS CORP. (US) 1992-05-05 US disclosed
US-4918192-A LUMINESCENCE; LABELS FOR IMMUNOASSAY CIBA CORNING DIAGNOSTICS CORP. (US) 1990-04-17 US disclosed
EP-0353971-A2 Acridinium esters and method for detection of an analyte using acridinium esters and liposomes Ciba Corning Diagnostics Corp. (US) 1990-02-07 EP disclosed
US-4745181-A STABLE LABELS FOR CHEMILUMINESCENT IMMUNOASSAY CIBA CORNING DIAGNOSTICS CORP. (US) 1988-05-17 US disclosed