Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | OGA | O60502 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | DNM1L | O00429 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13634266 | 0.85 | HRH3 (0.46) | HRH3PIK3CAMTOROGACTSB | |
| SCHEMBL13634265 | 0.80 | HRH3 (0.42) | HRH3OGACTSBCTSSCTSK | |
| SCHEMBL13634269 | 0.80 | OGA (0.41) | HRH3PIK3CAMTOROGACTSB | |
| SCHEMBL13162769 | 0.79 | HRH3 (0.47) | HRH3OGARAB9ASMN1; SMN2 | |
| SCHEMBL15888543 | 0.78 | HRH3 (0.48) | HRH3OGAMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL13162294 | 0.77 | ADK (0.35) | HRH3PIK3CAMTORMAPTRAB9A | |
| SCHEMBL22334855 | 0.76 | HRH4 (0.46) | HRH3OGACTSBCTSSCTSK | |
| SCHEMBL10279631 | 0.74 | OGA (0.48) | OGACTSBCTSSCTSKMAPT | |
| SCHEMBL13634205 | 0.74 | OGA (0.39) | HRH3OGACTSBCTSSCTSK | |
| SCHEMBL13634268 | 0.73 | HRH3 (0.45) | HRH3OGACTSBCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |