Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGA | O60502 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.35 |
| ▸ | RBP1 | P09455 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13634266 | 0.83 | HRH3 (0.46) | OGAHRH3CTSBCTSSCTSK | |
| SCHEMBL13634207 | 0.80 | HRH3 (0.43) | OGAHRH3CTSBCTSSCTSK | |
| SCHEMBL22334855 | 0.80 | HRH4 (0.46) | OGAHRH3CTSBCTSSCTSK | |
| SCHEMBL13634265 | 0.78 | HRH3 (0.42) | OGAHRH3CTSBCTSSCTSK | |
| SCHEMBL13634310 | 0.77 | PTGER1 (0.45) | OGAHRH3LMNAALDH1A1RAB9A | |
| SCHEMBL10279631 | 0.77 | OGA (0.48) | OGACTSBCTSSCTSKMAPT | |
| SCHEMBL15888540 | 0.76 | OGA (0.48) | OGAHRH3LMNAMAPTALDH1A1 | |
| SCHEMBL16603221 | 0.76 | F2RL3 (0.44) | F2RL3 | |
| SCHEMBL13162283 | 0.76 | LMNA (0.37) | LMNAMAPTALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL13634334 | 0.75 | DNM1L (0.42) | OGAHRH3CTSBCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |