Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGA | O60502 | 2/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | MAP3K12 | Q12852 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.31 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13634265 | 0.88 | HRH3 (0.42) | OGAHRH3CTSBCTSSCTSK | |
| SCHEMBL13634268 | 0.86 | HRH3 (0.45) | OGAHRH3CTSBCTSSCTSK | |
| SCHEMBL13634266 | 0.85 | HRH3 (0.46) | OGAHRH3CTSBCTSSCTSK | |
| SCHEMBL19012765 | 0.78 | OGA (0.41) | OGAHRH3CTSBCTSSCTSK | |
| SCHEMBL10279631 | 0.75 | OGA (0.48) | OGACTSBCTSSCTSKMAPT | |
| SCHEMBL13634334 | 0.74 | DNM1L (0.42) | OGAHRH3CTSBCTSSCTSK | |
| SCHEMBL13634269 | 0.74 | OGA (0.41) | OGAHRH3CTSBCTSSCTSK | |
| SCHEMBL3436059 | 0.74 | RAB9A (0.50) | OGAHRH3MAPTNPC1RAB9A | |
| SCHEMBL13634207 | 0.74 | HRH3 (0.43) | OGAHRH3CTSBCTSSCTSK | |
| SCHEMBL2770634 | 0.73 | PTGER1 (0.41) | OGAHRH3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |