SCHEMBL13634266

SCHEMBL13634266

CCc1csc(N2CCC(OC)CC2)n1

nearest known ligand 0.46

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 6/20 0.46
OGA O60502 2/20 0.42
CTSB P07858 1/20 0.41
CTSS P25774 1/20 0.41
CTSK P43235 1/20 0.41
MAPT P10636 2/20 0.38
RAB9A P51151 2/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
MAP4K4 O95819 1/20 0.35
PIK3CA P42336 1/20 0.35
MTOR P42345 1/20 0.35
NPC1 O15118 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13634265 0.92 HRH3 (0.42) HRH3OGACTSBCTSSCTSK
SCHEMBL13634207 0.85 HRH3 (0.43) HRH3OGACTSBCTSSCTSK
SCHEMBL13634205 0.85 OGA (0.39) HRH3OGACTSBCTSSCTSK
SCHEMBL13634268 0.83 HRH3 (0.45) HRH3OGACTSBCTSSCTSK
SCHEMBL13634269 0.83 OGA (0.41) HRH3OGACTSBCTSSCTSK
SCHEMBL22334855 0.82 HRH4 (0.46) HRH3OGACTSBCTSSCTSK
SCHEMBL3559247 0.80 HRH3 (0.55) HRH3OGAMAPTRAB9ASMN1; SMN2
SCHEMBL10279631 0.79 OGA (0.48) OGACTSBCTSSCTSKMAPT
SCHEMBL13634334 0.78 DNM1L (0.42) HRH3OGACTSBCTSSCTSK
SCHEMBL13612870 0.76 ALDH1A1 (0.50) OGACTSBCTSSCTSKMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8304547-B2 Azolecarboxamide compound or salt thereof ASTELLAS PHARMA INC. (JP) 2012-11-06 US disclosed