Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ELOVL1 | Q9BW60 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 5/20 | 0.33 |
| ▸ | NPC1 | O15118 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TYR | P14679 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.33 |
| ▸ | GCK | P35557 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.31 |
| ▸ | ACACB | O00763 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3550038 | 0.81 | ALDH1A1 (0.39) | ALDH1A1KDM4ELMNAGAAELOVL1 | |
| SCHEMBL3554233 | 0.76 | UCHL1 (0.36) | ALDH1A1RAB9ANPC1TYRMAPT | |
| SCHEMBL13999818 | 0.75 | RAB9A (0.45) | ALDH1A1KDM4ELMNAGAARAB9A | |
| SCHEMBL3435744 | 0.75 | UCHL1 (0.35) | ALDH1A1KDM4ELMNAGAAELOVL1 | |
| SCHEMBL13162307 | 0.75 | UCHL1 (0.36) | ALDH1A1KDM4ELMNAGAAELOVL1 | |
| SCHEMBL13662109 | 0.69 | MEN1 (0.56) | ALDH1A1KDM4ELMNAGAARAB9A | |
| SCHEMBL21267592 | 0.69 | ELOVL1 (0.38) | ALDH1A1KDM4ELMNAGAAELOVL1 | |
| SCHEMBL16603219 | 0.67 | SLC6A3 (0.39) | RAB9ANPC1GCKCNR1KCNH2 | |
| SCHEMBL17232503 | 0.67 | ELOVL1 (0.48) | ALDH1A1KDM4ELMNAGAAELOVL1 | |
| SCHEMBL13662016 | 0.65 | MEN1 (0.42) | ALDH1A1KDM4ELMNAGAARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |