Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 6/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.39 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13163168 | 0.92 | TSHR (0.40) | POLBLMNASMN1; SMN2TDP1HPGD | |
| SCHEMBL13270803 | 0.92 | HCAR2 (0.40) | SMN1; SMN2TP53HPGDCYP1A2CYP2C9 | |
| SCHEMBL13634787 | 0.92 | HCAR2 (0.40) | SMN1; SMN2TP53HPGDCYP1A2CYP2C9 | |
| SCHEMBL13634504 | 0.91 | PIM1 (0.37) | POLBLMNASMN1; SMN2 | |
| SCHEMBL13634890 | 0.90 | ALDH1A1 (0.37) | LMNASMN1; SMN2HPGDKDM4EMAPT | |
| SCHEMBL13634726 | 0.88 | GPR6 (0.38) | POLBLMNAHPGDKDM4EMAPT | |
| SCHEMBL13634625 | 0.87 | MEN1 (0.40) | SMN1; SMN2HPGDTSHRKDM4EHSD17B10 | |
| SCHEMBL13634544 | 0.87 | MEN1 (0.40) | SMN1; SMN2HPGDTSHRKDM4EHSD17B10 | |
| SCHEMBL13634745 | 0.86 | BCL3 (0.36) | POLBLMNAMAPTALDH1A1KMT2A | |
| SCHEMBL13634553 | 0.86 | BCL3 (0.36) | POLBLMNAMAPTALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |