Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 5/20 | 0.40 |
| ▸ | IRAK4 | Q9NWZ3 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.35 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.35 |
| ▸ | GPR6 | P46095 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13270803 | 1.00 | HCAR2 (0.40) | HCAR2IRAK4MEN1ALDH1A1KMT2A | |
| SCHEMBL13634860 | 0.92 | POLB (0.43) | ALDH1A1KMT2ASMN1; SMN2TP53CYP1A2 | |
| SCHEMBL13634770 | 0.91 | PIM1 (0.36) | HCAR2IRAK4CYP2C9GPR6 | |
| SCHEMBL13634890 | 0.90 | ALDH1A1 (0.37) | IRAK4ALDH1A1KMT2ASMN1; SMN2HPGD | |
| SCHEMBL13634544 | 0.88 | MEN1 (0.40) | IRAK4MEN1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL13634726 | 0.88 | GPR6 (0.38) | IRAK4MEN1ALDH1A1KMT2AHPGD | |
| SCHEMBL13634625 | 0.88 | MEN1 (0.40) | IRAK4MEN1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL13634553 | 0.88 | BCL3 (0.36) | IRAK4MEN1ALDH1A1KMT2AFGFR1 | |
| SCHEMBL13634745 | 0.88 | BCL3 (0.36) | IRAK4MEN1ALDH1A1KMT2AFGFR1 | |
| SCHEMBL13634630 | 0.87 | GPR6 (0.40) | IRAK4MEN1KMT2AGPR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |