Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 3/20 | 0.43 |
| ▸ | CNR2 | P34972 | 3/20 | 0.43 |
| ▸ | ADH1B | P00325 | 1/20 | 0.42 |
| ▸ | ADH1A | P07327 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2060435 | 0.91 | CRBN (0.56) | CRBNALDH1A1KDM4ENPC1RAB9A | |
| Water SCHEMBL28110279 | 0.89 | CRBN (0.55) | CRBNALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL28510668 | 0.84 | CRBN (0.51) | CRBNALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL4960760 | 0.84 | NPC1 (0.53) | CRBNALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL2771766 | 0.84 | CRBN (0.51) | CRBNALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL2771765 | 0.84 | CRBN (0.51) | CRBNALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL13161898 | 0.84 | ALDH1A1 (0.61) | CRBNALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL22720116 | 0.84 | ALDH1A1 (0.66) | CRBNALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL13634186 | 0.83 | RAB9A (0.59) | CRBNALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL22720137 | 0.83 | RAB9A (0.59) | CRBNALDH1A1KDM4ENPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |