Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3436051 | 0.86 | RAB9A (0.49) | ALDH1A1GAARAB9AMEN1KMT2A | |
| SCHEMBL3551333 | 0.82 | ALDH1A1 (0.41) | ALDH1A1TP53GAARAB9AMEN1 | |
| Hydrochloric Acid SCHEMBL2077470 | 0.81 | ALDH1A1 (0.40) | ALDH1A1TP53GAARAB9AMEN1 | |
| SCHEMBL3435890 | 0.77 | THRB (0.40) | ALDH1A1TP53GAARAB9AMEN1 | |
| SCHEMBL3436066 | 0.77 | THRB (0.40) | ALDH1A1TP53GAARAB9AMEN1 | |
| SCHEMBL3436205 | 0.76 | PTGDR2 (0.38) | ALDH1A1TP53GAARAB9AMEN1 | |
| SCHEMBL10277329 | 0.75 | ALDH1A1 (0.39) | ALDH1A1TP53GAARAB9AMEN1 | |
| SCHEMBL3557687 | 0.75 | PTGDR2 (0.42) | ALDH1A1TP53GAARAB9AMEN1 | |
| SCHEMBL3435935 | 0.74 | L3MBTL1 (0.37) | ALDH1A1MEN1KMT2AL3MBTL1PLA2G4A | |
| SCHEMBL13634203 | 0.73 | L3MBTL1 (0.36) | ALDH1A1TP53GAARAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2206707-B1 | AZOLECARBOXAMIDE COMPOUND OR SALT THEREOF | ASTELLAS PHARMA INC (JP) | 2014-07-23 | — | — | EP | disclosed |
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |