Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 2/20 | 0.34 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | LDHA | P00338 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3546215 | 0.78 | GRM5 (0.35) | GRM5MEN1KMT2A | |
| SCHEMBL3551333 | 0.77 | ALDH1A1 (0.41) | L3MBTL1ALDH1A1PLA2G4AMMP1MMP2 | |
| SCHEMBL13634203 | 0.77 | L3MBTL1 (0.36) | L3MBTL1ALDH1A1PLA2G4AMMP1MMP2 | |
| Hydrochloric Acid SCHEMBL2077470 | 0.76 | ALDH1A1 (0.40) | L3MBTL1ALDH1A1PLA2G4AMMP1MMP2 | |
| SCHEMBL3435890 | 0.75 | THRB (0.40) | L3MBTL1ALDH1A1PLA2G4AMMP1MMP2 | |
| SCHEMBL3436066 | 0.75 | THRB (0.40) | L3MBTL1ALDH1A1PLA2G4AMMP1MMP2 | |
| SCHEMBL15888636 | 0.75 | L3MBTL1 (0.41) | L3MBTL1ALDH1A1PLA2G4AMMP1MMP2 | |
| SCHEMBL13162589 | 0.75 | L3MBTL1 (0.41) | L3MBTL1ALDH1A1PLA2G4AMMP1MMP2 | |
| SCHEMBL13634208 | 0.75 | PLA2G4A (0.46) | L3MBTL1ALDH1A1PLA2G4AMMP1MMP2 | |
| SCHEMBL13634317 | 0.74 | ALDH1A1 (0.39) | L3MBTL1ALDH1A1PLA2G4AMMP1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8163746-B2 | Azolecarboxamide derivative | ASTELLAS PHARMA INC. (JP) | 2012-04-24 | — | — | US | disclosed |
| US-20090286766-A1 | AZOLECARBOXAMIDE DERIVATIVE | ASTELLAS PHARMA INC. (JP) | 2009-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090286766-A1 | AZOLECARBOXAMIDE DERIVATIVE | GPR17, NTRK1, TRPV1 | L3MBTL1 3267/4885ALDH1A1 975/4885PLA2G4A 3539/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.