Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.41 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.40 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.38 |
| ▸ | RET | P07949 | 3/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
| ▸ | AXL | P30530 | 1/20 | 0.35 |
| ▸ | MERTK | Q12866 | 1/20 | 0.35 |
| ▸ | TACR3 | P29371 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15888604 | 0.82 | DPP4 (0.45) | DPP4DPP9DPP8IP6K1RET | |
| SCHEMBL13638868 | 0.81 | DPP4 (0.38) | DPP4DPP9DPP8HRH3IP6K1 | |
| SCHEMBL13634227 | 0.81 | DPP4 (0.44) | DPP4DPP9DPP8IP6K1GPR119 | |
| SCHEMBL13634245 | 0.80 | PDE3B (0.41) | HRH3RET | |
| SCHEMBL13634319 | 0.78 | NAAA (0.48) | RET | |
| SCHEMBL13634244 | 0.75 | HRH3 (0.42) | HRH3AXLMERTK | |
| SCHEMBL13162856 | 0.75 | HRH3 (0.62) | DPP4DPP9DPP8HRH3IP6K1 | |
| SCHEMBL13634246 | 0.74 | OGA (0.36) | RET | |
| SCHEMBL13634302 | 0.74 | PDE3B (0.47) | RET | |
| SCHEMBL30222295 | 0.73 | DPP4 (0.52) | DPP4DPP9DPP8HRH3IP6K1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |