Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 8/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | NAAA | Q02083 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | AXL | P30530 | 1/20 | 0.33 |
| ▸ | MERTK | Q12866 | 1/20 | 0.33 |
| ▸ | TIPARP | Q7Z3E1 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | SCD | O00767 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2769952 | 0.82 | ALDH1A1 (0.39) | HRH3KCNH2GAACYP2C19ALDH1A1 | |
| SCHEMBL13634229 | 0.81 | HRH3 (0.40) | HRH3KCNH2GAACYP2C19ALDH1A1 | |
| SCHEMBL13162330 | 0.81 | HRH3 (0.42) | HRH3KCNH2GAACYP2C19ALDH1A1 | |
| SCHEMBL13634245 | 0.77 | PDE3B (0.41) | HRH3SCD | |
| SCHEMBL13634319 | 0.76 | NAAA (0.48) | NAAA | |
| SCHEMBL13634327 | 0.75 | DPP4 (0.41) | HRH3AXLMERTK | |
| SCHEMBL13634246 | 0.74 | OGA (0.36) | CYP2C19SCD | |
| SCHEMBL13162854 | 0.74 | HRH3 (0.54) | HRH3KCNH2GAACYP2C19ALDH1A1 | |
| SCHEMBL25113414 | 0.72 | HRH3 (0.50) | HRH3KCNH2ALDH1A1TIPARP | |
| SCHEMBL13634240 | 0.72 | HRH4 (0.33) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |