Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 4/20 | 0.40 |
| ▸ | MTOR | P42345 | 10/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.38 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.35 |
| ▸ | ATR | Q13535 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13634339 | 0.80 | HTR3A (0.41) | HTR3AMTORPIK3CAAURKAPDPK1 | |
| SCHEMBL13634370 | 0.75 | MAPK1 (0.39) | KCNH2 | |
| SCHEMBL13634304 | 0.70 | HRH4 (0.38) | HTR3AKCNH2 | |
| SCHEMBL21029956 | 0.69 | MTOR (0.49) | HTR3AMTORPIK3CAAURKAPDPK1 | |
| SCHEMBL20692864 | 0.69 | MTOR (0.49) | HTR3AMTORPIK3CAAURKAPDPK1 | |
| SCHEMBL13163110 | 0.67 | PDK1 (0.39) | HTR3AMTOR | |
| SCHEMBL22775348 | 0.67 | AURKA (0.41) | HTR3AMTORPIK3CAAURKAPDPK1 | |
| SCHEMBL22775349 | 0.67 | AURKA (0.41) | HTR3AMTORPIK3CAAURKAPDPK1 | |
| SCHEMBL22773872 | 0.67 | AURKA (0.41) | HTR3AMTORPIK3CAAURKAPDPK1 | |
| SCHEMBL4201820 | 0.67 | AURKA (0.41) | HTR3AMTORPIK3CAAURKAPDPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |