SCHEMBL13634304

SCHEMBL13634304

CCc1coc(N2CCC(F)CC2)n1

nearest known ligand 0.38

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
HRH4 Q9H3N8 3/20 0.38
HRH3 Q9Y5N1 2/20 0.33
HTR3A P46098 1/20 0.32
KCNH2 Q12809 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13634211 0.91 HRH4 (0.39) HRH4HRH3HTR3AKCNH2
SCHEMBL13634305 0.86 GPR119 (0.43) HRH4HRH3HTR3AKCNH2
SCHEMBL13634370 0.83 MAPK1 (0.39) KCNH2
SCHEMBL13634262 0.82 HRH4 (0.35) HRH4HRH3
SCHEMBL13634313 0.80 CNR2 (0.37) HRH4HRH3
SCHEMBL13612636 0.80 HTR6 (0.44) HRH4HTR3A
SCHEMBL13634326 0.79 GPR119 (0.34) HRH4
SCHEMBL13162793 0.78 KDM4E (0.35) HTR3AKCNH2
SCHEMBL13634239 0.78 AOC3 (0.35) HRH4HRH3
SCHEMBL13634240 0.77 HRH4 (0.33) HRH4HRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8304547-B2 Azolecarboxamide compound or salt thereof ASTELLAS PHARMA INC. (JP) 2012-11-06 US disclosed