Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | NPY1R | P25929 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.35 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13634304 | 0.83 | HRH4 (0.38) | KCNH2 | |
| SCHEMBL15349077 | 0.83 | PIK3CA (0.40) | ARPOLBCXCR4ELANE | |
| SCHEMBL13612636 | 0.83 | HTR6 (0.44) | — | |
| SCHEMBL13634305 | 0.79 | GPR119 (0.43) | MAPK1SMN1; SMN2KCNH2 | |
| SCHEMBL15348882 | 0.77 | F2RL3 (0.37) | MAPK1SMN1; SMN2KMT2AMEN1HSD17B10 | |
| SCHEMBL24375507 | 0.77 | KMT2A (0.46) | MAPK1SMN1; SMN2KMT2AMEN1TSHR | |
| SCHEMBL13634320 | 0.75 | HTR3A (0.40) | KCNH2 | |
| SCHEMBL13634210 | 0.75 | HRH3 (0.33) | — | |
| SCHEMBL24375918 | 0.74 | SMN1; SMN2 (0.36) | MAPK1SMN1; SMN2NUDT1KMT2AMEN1 | |
| SCHEMBL24375907 | 0.74 | SMN1; SMN2 (0.36) | MAPK1SMN1; SMN2NUDT1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |