SCHEMBL13634357

SCHEMBL13634357

CC(=O)NCc1nc(C(=O)O)cs1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.54
MMP1 P03956 1/20 0.47
MMP2 P08253 1/20 0.47
MMP9 P14780 1/20 0.47
MMP13 P45452 1/20 0.47
LIPG Q9Y5X9 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46
ALOX15 P16050 1/20 0.44
FPR3 P25089 2/20 0.41
FPR2 P25090 2/20 0.41
KMT2A Q03164 2/20 0.41
ALDH1A1 P00352 2/20 0.41
KDM4E B2RXH2 2/20 0.41
POLB P06746 2/20 0.40
MEN1 O00255 1/20 0.40
MAPT P10636 1/20 0.40
HSD17B10 Q99714 1/20 0.40
HDAC1 Q13547 1/20 0.40
HDAC8 Q9BY41 1/20 0.40
HDAC6 Q9UBN7 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9298064 0.88 FPR2 (0.50) NPSR1ALOX15FPR3FPR2KMT2A
SCHEMBL22876069 0.85 NPSR1 (0.45) L3MBTL1NPSR1ALOX15FPR3FPR2
SCHEMBL13162586 0.84 LIPG (0.45) L3MBTL1MMP1MMP2MMP9MMP13
SCHEMBL14076069 0.83 MMP1 (0.47) L3MBTL1MMP1MMP2MMP9MMP13
SCHEMBL13270733 0.83 MMP1 (0.49) L3MBTL1MMP1MMP2MMP9MMP13
SCHEMBL9298456 0.83 NPSR1 (0.42) L3MBTL1NPSR1ALOX15FPR3FPR2
SCHEMBL5178524 0.79 RAB9A (0.50) NPSR1ALOX15KMT2AALDH1A1KDM4E
SCHEMBL1852466 0.79 HDAC3 (0.52) L3MBTL1MMP1MMP2MMP9MMP13
SCHEMBL27000058 0.79 MMP1 (0.46) L3MBTL1MMP1MMP2MMP9MMP13
SCHEMBL7984987 0.78 KDM4E (0.53) MMP1MMP2MMP9MMP13LIPG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8304547-B2 Azolecarboxamide compound or salt thereof ASTELLAS PHARMA INC. (JP) 2012-11-06 US disclosed