Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | MMP1 | P03956 | 1/20 | 0.52 |
| ▸ | MMP2 | P08253 | 1/20 | 0.52 |
| ▸ | MMP9 | P14780 | 1/20 | 0.52 |
| ▸ | MMP13 | P45452 | 1/20 | 0.52 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.52 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7260803 | 0.83 | RAB9A (0.67) | KDM4ENPC1MMP1MMP13HPGD | |
| SCHEMBL2711084 | 0.82 | NPC1 (0.58) | KDM4ENPC1HPGDMAPTMAPK1 | |
| SCHEMBL2227256 | 0.81 | MAPT (0.67) | KDM4ENPC1HPGDHDAC1HDAC6 | |
| SCHEMBL7984989 | 0.79 | KDM4E (0.50) | KDM4ENPC1ENPP2HPGDHDAC1 | |
| SCHEMBL14076069 | 0.78 | MMP1 (0.47) | KDM4EMMP1MMP2MMP9MMP13 | |
| SCHEMBL13634357 | 0.78 | L3MBTL1 (0.54) | KDM4EMMP1MMP2MMP9MMP13 | |
| SCHEMBL1491309 | 0.78 | MAPT (0.57) | KDM4ENPC1ENPP2HDAC1HDAC6 | |
| SCHEMBL3165764 | 0.77 | MMP2 (0.53) | MMP1MMP2MMP9MMP13LIPG | |
| SCHEMBL13162586 | 0.76 | LIPG (0.45) | KDM4ENPC1MMP1MMP2MMP9 | |
| SCHEMBL13270733 | 0.74 | MMP1 (0.49) | KDM4EMMP1MMP2MMP9MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001027095-A1 | METHOD FOR PRODUCING 2-(N-BOC-AMINOMETHYL)-THIAZOL-4-CARBOXYLIC ACID | BASF AKTIENGESELLSCHAFT (DE) | 2001-04-19 | — | — | WO | disclosed |