Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.46 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.46 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13753816 | 0.87 | HPGD (0.49) | ALDH1A1HPGDHSD17B10SMN1; SMN2MAPK1 | |
| SCHEMBL8323157 | 0.84 | HPGD (0.56) | POLBALDH1A1HPGDHSD17B10SMN1; SMN2 | |
| SCHEMBL7104333 | 0.83 | L3MBTL1 (0.48) | POLBTHRBRECQLTDP1L3MBTL1 | |
| SCHEMBL7813262 | 0.83 | RECQL (0.68) | POLBTHRBRECQLTDP1L3MBTL1 | |
| SCHEMBL18645554 | 0.82 | NAAA (0.57) | POLBTHRBRECQLTDP1L3MBTL1 | |
| SCHEMBL28456551 | 0.81 | L3MBTL1 (0.49) | POLBTHRBRECQLTDP1L3MBTL1 | |
| SCHEMBL12121132 | 0.81 | POLB (0.53) | POLBTHRBRECQLTDP1L3MBTL1 | |
| SCHEMBL13753858 | 0.80 | POLB (0.59) | POLBTHRBRECQLTDP1L3MBTL1 | |
| SCHEMBL7005423 | 0.79 | ALDH1A1 (0.46) | ALDH1A1HPGDHSD17B10SMN1; SMN2MAPK1 | |
| SCHEMBL29016441 | 0.79 | MAPT (0.57) | THRBTDP1ALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017161119-A1 | SMALL MOLECULES AGAINST CEREBLON TO ENHANCE EFFECTOR T CELL FUNCTION | H. LEE MOFFITT CANCER CENTER & RESEARCH INSTITUTE, INC. (US) | 2017-09-21 | — | — | WO | disclosed |
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |
| US-7576117-B1 | Cyclic amine CCR3 antagonist | TEIJIN LIMITED (JP) | 2009-08-18 | — | — | US | disclosed |