Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE2 | O96020 | 1/20 | 0.48 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.48 |
| ▸ | CDK2 | P24941 | 1/20 | 0.48 |
| ▸ | GSK3B | P49841 | 1/20 | 0.48 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 3/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | JAK1 | P23458 | 1/20 | 0.42 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13163122 | 0.90 | CDK2 (0.44) | CCNE2CCNE1CDK2GSK3BPTPN11 | |
| SCHEMBL13638850 | 0.89 | KMT2A (0.42) | CCNE2CCNE1CDK2GSK3BPTPN11 | |
| SCHEMBL13162588 | 0.89 | MAPT (0.45) | KMT2AALDH1A1CYP11B1CYP11B2LMNA | |
| SCHEMBL15888569 | 0.88 | CCNE2 (0.45) | CCNE2CCNE1CDK2GSK3BPTPN11 | |
| SCHEMBL13163944 | 0.85 | HIF1A (0.51) | CCNE2CCNE1CDK2GSK3BKMT2A | |
| SCHEMBL13634715 | 0.82 | IRAK4 (0.44) | CDK2PTPN11KMT2ANAMPTALDH1A1 | |
| SCHEMBL13162254 | 0.80 | FAAH (0.53) | CCNE2CCNE1CDK2GSK3BPTPN11 | |
| SCHEMBL13163941 | 0.78 | ALDH1A1 (0.53) | KMT2AALDH1A1GRM2JAK2JAK1 | |
| SCHEMBL13634878 | 0.78 | IRAK4 (0.43) | GRM2JAK2JAK1LRRK2 | |
| SCHEMBL13634408 | 0.77 | GRM2 (0.43) | KMT2AALDH1A1GRM2JAK2JAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |