Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | DRD3 | P35462 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.48 |
| ▸ | HTR2C | P28335 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13638973 | 0.91 | GRM2 (0.49) | KDM4EALDH1A1GAAMAPTHPGD | |
| SCHEMBL13163981 | 0.87 | KDM4E (0.52) | KDM4EALDH1A1GAAMAPTHPGD | |
| SCHEMBL13634403 | 0.85 | DRD4 (0.47) | KDM4EALDH1A1MAPTDRD3MEN1 | |
| SCHEMBL2774659 | 0.82 | ALDH1A1 (0.59) | KDM4EALDH1A1GAAMAPTHPGD | |
| SCHEMBL13162596 | 0.81 | DRD4 (0.50) | SIGMAR1GRM2DRD4DRD2 | |
| Hydrochloric Acid SCHEMBL2769406 | 0.81 | ALDH1A1 (0.58) | KDM4EALDH1A1GAAMAPTHPGD | |
| SCHEMBL13634374 | 0.81 | ALDH1A1 (0.43) | KDM4EALDH1A1GAAMAPTHPGD | |
| SCHEMBL13634184 | 0.79 | ALDH1A1 (0.56) | KDM4EALDH1A1GAAMAPTHPGD | |
| SCHEMBL13163940 | 0.78 | KDM4E (0.54) | KDM4EALDH1A1GAAMAPTHPGD | |
| SCHEMBL13634159 | 0.78 | KDM4E (0.54) | KDM4EALDH1A1GAAMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |