Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 14/20 | 0.47 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13162348 | 0.92 | DRD4 (0.49) | DRD4SIRT6GRM2SIGMAR1DRD2 | |
| SCHEMBL13162333 | 0.89 | SIRT6 (0.47) | DRD4SIRT6KDM4EGRM2ALDH1A1 | |
| SCHEMBL15888631 | 0.89 | DRD4 (0.47) | DRD4KDM4EGRM2ALDH1A1LMNA | |
| SCHEMBL13634376 | 0.85 | KDM4E (0.50) | DRD4KDM4EGRM2ALDH1A1LMNA | |
| SCHEMBL2771503 | 0.84 | SMN1; SMN2 (0.53) | SIRT6ALDH1A1LMNAMAPTMAPK1 | |
| SCHEMBL13270425 | 0.83 | DRD4 (0.50) | DRD4GRM2SIGMAR1DRD2 | |
| SCHEMBL13634232 | 0.82 | SIRT6 (0.61) | SIRT6ALDH1A1LMNAMAPTPKM | |
| SCHEMBL13634181 | 0.81 | SIRT6 (0.49) | SIRT6KDM4EALDH1A1LMNAMAPT | |
| SCHEMBL13634150 | 0.81 | SIRT6 (0.55) | SIRT6KDM4EALDH1A1LMNAMAPT | |
| SCHEMBL13163912 | 0.81 | SIRT6 (0.48) | SIRT6KDM4EGRM2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |