Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | IDH1 | O75874 | 1/20 | 0.41 |
| ▸ | LGMN | Q99538 | 2/20 | 0.40 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.40 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.40 |
| ▸ | AKT1 | P31749 | 1/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 4/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13638828 | 0.90 | ALDH1A1 (0.42) | ALDH1A1KDM4EMAPTHPGDHSD17B10 | |
| SCHEMBL13634232 | 0.84 | SIRT6 (0.61) | ALDH1A1MAPTHPGDSIRT6SMN1; SMN2 | |
| SCHEMBL13634376 | 0.81 | KDM4E (0.50) | ALDH1A1KDM4EMAPTHPGDHSD17B10 | |
| SCHEMBL9344830 | 0.80 | LGMN (0.54) | ALDH1A1KDM4EMAPTHPGDHSD17B10 | |
| SCHEMBL29209070 | 0.80 | RAD52 (0.54) | ALDH1A1KDM4EMAPTHSD17B10GAA | |
| SCHEMBL20509930 | 0.75 | IP6K1 (0.68) | ALDH1A1KDM4EMAPTHPGDHSD17B10 | |
| SCHEMBL40467 | 0.74 | IP6K1 (0.66) | ALDH1A1KDM4EMAPTHPGDHSD17B10 | |
| SCHEMBL26783813 | 0.74 | CHEK1 (0.37) | ALDH1A1MAPTIDH1SIRT6CHEK1 | |
| SCHEMBL31438074 | 0.74 | MAPT (0.46) | ALDH1A1KDM4EMAPTHSD17B10GAA | |
| SCHEMBL27170976 | 0.74 | MCHR1 (0.45) | ALDH1A1KDM4EMAPTHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |