Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13634408 | 0.87 | GRM2 (0.43) | LMNAKMT2ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL13634373 | 0.85 | KMT2A (0.57) | LMNAMEN1KMT2ASMN1; SMN2CYP2C19 | |
| SCHEMBL13634356 | 0.85 | MAPT (0.44) | LMNAMEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL13163913 | 0.84 | SIRT6 (0.47) | LMNAMEN1KMT2ASIRT6MAPT | |
| SCHEMBL15888568 | 0.84 | LMNA (0.44) | LMNAMEN1KMT2ASMN1; SMN2CYP2C19 | |
| SCHEMBL13162588 | 0.79 | MAPT (0.45) | LMNAMEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL13634236 | 0.79 | MEN1 (0.61) | LMNAMEN1KMT2ASMN1; SMN2CYP2C19 | |
| SCHEMBL13270391 | 0.79 | LMNA (0.41) | LMNAMEN1KMT2ASMN1; SMN2CYP2C19 | |
| SCHEMBL13162600 | 0.77 | KMT2A (0.49) | LMNAKMT2AMAPTALDH1A1GRM2 | |
| SCHEMBL13162385 | 0.77 | KMT2A (0.48) | KMT2AGRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |