Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | DTYMK | P23919 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | KCNJ1 | P48048 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | JAK1 | P23458 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13163913 | 0.88 | SIRT6 (0.47) | MAPTGRM2ALDH1A1KDM4ENPC1 | |
| SCHEMBL13634404 | 0.85 | LMNA (0.46) | MAPTGRM2ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL13164038 | 0.84 | GRM2 (0.45) | GRM2KDM4ESMN1; SMN2NPC1RAB9A | |
| SCHEMBL13162588 | 0.80 | MAPT (0.45) | MAPTALDH1A1SMN1; SMN2MAPK1LMNA | |
| SCHEMBL28760049 | 0.76 | MAPT (0.42) | MAPTGRM2CYP19A1DTYMKALDH1A1 | |
| SCHEMBL13163914 | 0.74 | L3MBTL1 (0.50) | MAPTDTYMKALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL13270618 | 0.74 | HTR1A (0.54) | MAPTDTYMKALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL15888568 | 0.74 | LMNA (0.44) | MAPTALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL13163941 | 0.74 | ALDH1A1 (0.53) | MAPTGRM2ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL13163139 | 0.74 | GRM2 (0.43) | MAPTGRM2ALDH1A1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2206707-B1 | AZOLECARBOXAMIDE COMPOUND OR SALT THEREOF | ASTELLAS PHARMA INC (JP) | 2014-07-23 | — | — | EP | disclosed |
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |